Derivation of the shrinkage estimates of quantitative trait locus effects.
نویسنده
چکیده
The shrinkage estimate of a quantitative trait locus (QTL) effect is the posterior mean of the QTL effect when a normal prior distribution is assigned to the QTL. This note gives the derivation of the shrinkage estimate under the multivariate linear model. An important lemma regarding the posterior mean of a normal likelihood combined with a normal prior is introduced. The lemma is then used to derive the Bayesian shrinkage estimates of the QTL effects.
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ورودعنوان ژورنال:
- Genetics
دوره 177 2 شماره
صفحات -
تاریخ انتشار 2007